A microphysiological model of human trophoblast invasion during implantation

Normal and abnormal pregnancy is challenging to study and involves complex interactions between maternal and fetal cells. Here the authors present an implantation-on-a-chip device capable of modeling trophoblast invasion, a process critical to the establishment of pregnancy.

Bibliographic Details
Main Authors: Ju Young Park, Sneha Mani, Geremy Clair, Heather M. Olson, Vanessa L. Paurus, Charles K. Ansong, Cassidy Blundell, Rachel Young, Jessica Kanter, Scott Gordon, Alex Y. Yi, Monica Mainigi, Dan Dongeun Huh
Format: Article
Language:English
Published: Nature Portfolio 2022-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-28663-4