NPAS2 Contributes to Liver Fibrosis by Direct Transcriptional Activation of Hes1 in Hepatic Stellate Cells

NPAS2 Contributes to Liver Fibrosis by Direct Transcriptional Activation of Hes1 in Hepatic Stellate Cells

Recently, emerging evidence shows that dysregulation of circadian genes is closely associated with liver fibrosis. However, how dysregulation of circadian genes promotes liver fibrosis is unknown. In this study, we show that neuronal PAS domain protein 2 (NPAS2), one of the core circadian molecules...

Full description

Bibliographic Details
Main Authors: Tao Yang, Peng Yuan, Yi Yang, Ning Liang, Qian Wang, Jing Li, Rui Lu, Hongxin Zhang, Jiao Mu, Zhaoyong Yan, Hulin Chang
Format: Article
Language:English
Published: Elsevier 2019-12-01
Series:Molecular Therapy: Nucleic Acids
Online Access:http://www.sciencedirect.com/science/article/pii/S216225311930335X

Internet

http://www.sciencedirect.com/science/article/pii/S216225311930335X

Similar Items