Apigenin Isolated from the Medicinal Plant Elsholtzia rugulosa Prevents β-Amyloid 25–35-Induces Toxicity in Rat Cerebral Microvascular Endothelial Cells

Endothelial cells of cerebral capillaries forming the blood-brain barrier play an important role in the pathogenesis and therapy of Alzheimer’s disease. Amyloid-β peptides are key pathological elements in the development of this disease. Apigenin (4’,5,7-tetrahydroxyflavone) is a plant flavonoid and...

Full description

Bibliographic Details
Main Authors: Qingshan Liu, Jianguang Li, Yu Chu, Yong Bian, Xifeng Sun, Xin Yan, Huijun Sun, Lin Hou, Le Zhao
Format: Article
Language:English
Published: MDPI AG 2011-05-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/16/5/4005/