Interleukin-1 receptor associated kinase 1 (IRAK1) is epigenetically activated in luminal epithelial cells in prostate cancer

Interleukin-1 receptor associated kinase 1 (IRAK1) is epigenetically activated in luminal epithelial cells in prostate cancer

The use of immune adjuvants such as toll-like receptor (TLR) agonists reflects a novel strategy in prostate cancer (PCa) therapy. However, interleukin-1 receptor associated kinase 1 (IRAK1), a central effector of TLR signaling, has been shown to be responsible for resistance to radiation-induced tum...

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Bibliographic Details
Main Authors: Undraga Schagdarsurengin, Vanessa Breiding, Maria Loose, Florian Wagenlehner, Temuujin Dansranjav
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Oncology
Subjects:
prostate cancer
IRAK1
Myddosome complex
epigenetic regulation
DNA methylation
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.991368/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2022.991368/full

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