Brain-derived neurotrophic factor gene polymorphism affects cognitive function and neurofilament light chain level in patients with subcortical ischaemic vascular dementia

Brain-derived neurotrophic factor gene polymorphism affects cognitive function and neurofilament light chain level in patients with subcortical ischaemic vascular dementia

ObjectiveTo investigate the effects of brain-derived neurotrophic factor (BDNF) gene polymorphism on cognitive function, neuroimaging and blood biological markers in patients with subcortical ischaemic vascular dementia (SIVD).MethodsA total of 81 patients with SIVD were included. According to their...

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Bibliographic Details
Main Authors: Xiaojuan Yao, Guotao Yang, Tingting Fang, Zhuo Tian, Yunyao Lu, Feifan Chen, Ping Che, Jingshan Chen, Nan Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Aging Neuroscience
Subjects:
brain-derived neurotrophic factor
subcortical ischaemic vascular dementia
cognitive function
small vessel disease
neurofilament light chain
polymorphism
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2023.1244191/full

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https://www.frontiersin.org/articles/10.3389/fnagi.2023.1244191/full

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