Exosomal microRNA-107 reverses chemotherapeutic drug resistance of gastric cancer cells through HMGA2/mTOR/P-gp pathway

Abstract Background RNA cargo in exosomes, especially microRNAs (miRNAs), play an important role in the chemotherapy drug resistance of human cancers. However, the role and mechanism of exosomal miR-107 on multidrug resistance of gastric cancer cells was still not clear. In this study, we sought to...

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Bibliographic Details
Main Authors: Lu Jiang, Yan Zhang, Linghui Guo, Chaoyang Liu, Pan Wang, Weihong Ren
Format: Article
Language:English
Published: BMC 2021-12-01
Series:BMC Cancer
Subjects:
Online Access:https://doi.org/10.1186/s12885-021-09020-y