IKACh is constitutively active via PKC epsilon in aging mediated atrial fibrillation
Summary: Atrial fibrillation (AF), the most common abnormal heart rhythm, is a major cause for stroke. Aging is a significant risk factor for AF; however, specific ionic pathways that can elucidate how aging leads to AF remain elusive. We used young and old wild-type and PKC epsilon- (PKCϵ) knockout...
Main Authors: | Mengmeng Chang, Kirin D. Gada, Bojjibabu Chidipi, Athanasios Tsalatsanis, Justin Gibbons, Elizabeth Remily-Wood, Diomedes E. Logothetis, Jenna Oberstaller, Sami F. Noujaim |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2022-11-01
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Series: | iScience |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S258900422201714X |
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