The Oxygen-Generating Calcium Peroxide-Modified Magnetic Nanoparticles Attenuate Hypoxia-Induced Chemoresistance in Triple-Negative Breast Cancer

The Oxygen-Generating Calcium Peroxide-Modified Magnetic Nanoparticles Attenuate Hypoxia-Induced Chemoresistance in Triple-Negative Breast Cancer

Cancer response to chemotherapy is regulated not only by intrinsic sensitivity of cancer cells but also by tumor microenvironment. Tumor hypoxia, a condition of low oxygen level in solid tumors, is known to increase the resistance of cancer cells to chemotherapy. Triple-negative breast cancer (TNBC)...

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Bibliographic Details
Main Authors: Fong-Yu Cheng, Chia-Hsin Chan, Bour-Jr Wang, Ya-Ling Yeh, Ying-Jan Wang, Hui-Wen Chiu
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Cancers
Subjects:
hypoxia
nanocarriers
chemoresistance
triple-negative breast cancer
autophagy
Online Access:https://www.mdpi.com/2072-6694/13/4/606

Internet

https://www.mdpi.com/2072-6694/13/4/606

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