Polyoma virus-induced osteosarcomas in inbred strains of mice: host determinants of metastasis.
The mouse polyoma virus induces a broad array of solid tumors in mice of many inbred strains. In most strains tumors grow rapidly but fail to metastasize. An exception has been found in the Czech-II/Ei mouse in which bone tumors metastasize regularly to the lung. These tumors resemble human osteosar...
Main Authors: | , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2010-01-01
|
Series: | PLoS Pathogens |
Online Access: | http://europepmc.org/articles/PMC2809769?pdf=render |