Therapeutic strategies targeting folate receptor α for ovarian cancer

Therapeutic strategies targeting folate receptor α for ovarian cancer

Epithelial ovarian cancer (EOC) is the deadliest gynecological cancer, and presents a major clinical challenge due to limited treatment options. Folate receptor alpha (FRα), encoded by the FOLR1 gene, is an attractive therapeutically target due to its prevalent and high expression in EOC cells. Rece...

Full description

Bibliographic Details
Main Authors: Jia Mai, Limei Wu, Ling Yang, Ting Sun, Xiaojuan Liu, Rutie Yin, Yongmei Jiang, Jinke Li, Qintong Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Immunology
Subjects:
ovarian cancer
folate receptor α
FOLR1
mirvetuximab soravtansine
MIRV
Elahere
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1254532/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1254532/full

Similar Items