Ethyl Methane Sulfonate and Sodium Azide-Mediated Chemical and X-ray-Mediated Physical Mutagenesis Positively Regulate <i>Peroxidase 1</i> Gene Activity and Biosynthesis of Antineoplastic Vinblastine in <i>Catharanthus roseus</i>

Ethyl Methane Sulfonate and Sodium Azide-Mediated Chemical and X-ray-Mediated Physical Mutagenesis Positively Regulate <i>Peroxidase 1</i> Gene Activity and Biosynthesis of Antineoplastic Vinblastine in <i>Catharanthus roseus</i>

<i>Catharanthus roseus</i> synthesizes bioactive therapeutic metabolites, known as monoterpenoid indole alkaloids (MIAs), including antineoplastic vinblastine and vincristine, which have high global demand, and antihypertensive ajmalicine, a serpentine. However, the in planta biosynthesi...

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Bibliographic Details
Main Authors: Vyoma Mistry, Pragya Tiwari, Paresh Patel, Gajendra Singh Vishwakarma, Geung-Joo Lee, Abhishek Sharma
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Plants
Subjects:
<i>Catharanthus roseus</i>
chemical mutagenesis
ethyl methane sulfonate
monoterpenoid indole alkaloids
sodium azide
<i>PRX1</i>
Online Access:https://www.mdpi.com/2223-7747/11/21/2885

Internet

https://www.mdpi.com/2223-7747/11/21/2885

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