Diagnostic value of skin RT-QuIC in Parkinson’s disease: a two-laboratory study

Diagnostic value of skin RT-QuIC in Parkinson’s disease: a two-laboratory study

Abstract Skin α-synuclein deposition is considered a potential biomarker for Parkinson’s disease (PD). Real-time quaking-induced conversion (RT-QuIC) is a novel, ultrasensitive, and efficient seeding assay that enables the detection of minute amounts of α-synuclein aggregates. We aimed to determine...

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Bibliographic Details
Main Authors: Anastasia Kuzkina, Connor Bargar, Daniela Schmitt, Jonas Rößle, Wen Wang, Anna-Lena Schubert, Curtis Tatsuoka, Steven A. Gunzler, Wen-Quan Zou, Jens Volkmann, Claudia Sommer, Kathrin Doppler, Shu G. Chen
Format: Article
Language:English
Published: Nature Portfolio 2021-11-01
Series:npj Parkinson's Disease
Online Access:https://doi.org/10.1038/s41531-021-00242-2

Internet

https://doi.org/10.1038/s41531-021-00242-2

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