Olive Mill Wastewater Inhibits Growth and Proliferation of Cisplatin- and Gemcitabine-Resistant Bladder Cancer Cells In Vitro by Down-Regulating the Akt/mTOR-Signaling Pathway

Olive Mill Wastewater Inhibits Growth and Proliferation of Cisplatin- and Gemcitabine-Resistant Bladder Cancer Cells In Vitro by Down-Regulating the Akt/mTOR-Signaling Pathway

Bladder cancer patients whose tumors develop resistance to cisplatin-based chemotherapy often turn to natural, plant-derived products. Beneficial effects have been particularly ascribed to polyphenols, although their therapeutic relevance when resistance has developed is not clear. The present study...

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Bibliographic Details
Main Authors: Jochen Rutz, Sebastian Maxeiner, Eva Juengel, Felix K.-H. Chun, Igor Tsaur, Roman A. Blaheta
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Nutrients
Subjects:
olive mill wastewater (OMWW)
bladder cancer
tumor growth
Akt-mTOR signaling
CDK-cyclin axis
Online Access:https://www.mdpi.com/2072-6643/14/2/369

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https://www.mdpi.com/2072-6643/14/2/369

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