The Glycoprotein and Nucleocapsid Protein of Hantaviruses Manipulate Autophagy Flux to Restrain Host Innate Immune Responses

Summary: Hantavirus infection, which causes severe zoonotic diseases with high mortality in humans, has become a global public health concern. Here, we demonstrate that Hantaan virus (HTNV), the prevalent prototype of the hantavirus in Asia, can restrain innate immune responses by manipulating host...

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Bibliographic Details
Main Authors: Kerong Wang, Hongwei Ma, He Liu, Wei Ye, Zhuo Li, Linfeng Cheng, Liang Zhang, Yingfeng Lei, Lixin Shen, Fanglin Zhang
Format: Article
Language:English
Published: Elsevier 2019-05-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719305340