UPF1: From mRNA Surveillance to Protein Quality Control

UPF1: From mRNA Surveillance to Protein Quality Control

Selective recognition and removal of faulty transcripts and misfolded polypeptides are crucial for cell viability. In eukaryotic cells, nonsense-mediated mRNA decay (NMD) constitutes an mRNA surveillance pathway for sensing and degrading aberrant transcripts harboring premature termination codons (P...

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Bibliographic Details
Main Authors: Hyun Jung Hwang, Yeonkyoung Park, Yoon Ki Kim
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Biomedicines
Subjects:
nonsense-mediated mRNA decay
UPF1
aggresome
CTIF
mRNA surveillance
protein quality control
Online Access:https://www.mdpi.com/2227-9059/9/8/995

Internet

https://www.mdpi.com/2227-9059/9/8/995

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