Propionate restores disturbed gut microbiota induced by methotrexate in Rheumatoid Arthritis: From clinic to experiments

Propionate restores disturbed gut microbiota induced by methotrexate in Rheumatoid Arthritis: From clinic to experiments

Objective: Gut toxicity of methotrexate restricts its long-term clinical application in patients with rheumatoid arthritis (RA). However, the disturbed gut microbiota especially beneficial bacteria induced by methotrexate remain unclear, and the way to alleviate the disturbances is limited. The aim...

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Bibliographic Details
Main Authors: Zhexin Fan, Bo Yang, R. Paul Ross, Catherine Stanton, Feng Zhang, Jian Sun, Jianxin Zhao, Hao Zhang, Wei Chen
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:Journal of King Saud University: Science
Subjects:
Gut microbiota
Lactobacilli community
Bifidobacterial community
Propionate
Methotrexate
Rheumatoid arthritis
Online Access:http://www.sciencedirect.com/science/article/pii/S1018364721002068

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http://www.sciencedirect.com/science/article/pii/S1018364721002068

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