Maintenance of a central high frequency synapse in the absence of synaptic activity

Activity has long been considered essential for circuit formation and maintenance. This view has recently been challenged by proper synaptogenesis and only mildly affected synapse maintenance in the absence of synaptic activity in forebrain neurons. Here, we investigated whether synaptic activity is...

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Bibliographic Details
Main Authors: Sascha Lessle, Lena Ebbers, Yvette Dörflinger, Simone Hoppe, Michaela Kaiser, Hans Gerd Nothwang, Christoph Körber
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-11-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2024.1404206/full