Triple modal treatment comprising with proton beam radiation, hyperthermia, and gemcitabine/nab-paclitaxel for locally advanced pancreatic cancer: a phase I/II study protocol (TT-LAP trial)

Triple modal treatment comprising with proton beam radiation, hyperthermia, and gemcitabine/nab-paclitaxel for locally advanced pancreatic cancer: a phase I/II study protocol (TT-LAP trial)

Abstract Background Locally advanced pancreatic ductal adenocarcinoma (PDAC), accounting for about 30% of PDAC patients, is difficult to cure by radical resection or systemic chemotherapy alone. A multidisciplinary strategy is required and our TT-LAP trial aims to evaluate whether triple-modal treat...

Full description

Bibliographic Details
Main Authors: Osamu Shimomura, Masato Endo, Hirokazu Makishima, Takeshi Yamada, Shinji Hashimoto, Haruko Numajiri, Yoshihiro Miyazaki, Manami Doi, Kinji Furuya, Kazuhiro Takahashi, Toshikazu Moriwaki, Naoyuki Hasegawa, Yoshiyuki Yamamoto, Yusuke Niisato, Mariko Kobayashi, Masashi Mizumoto, Kei Nakai, Takashi Saito, Sodai Hoshiai, Tsukasa Saida, Bryan J. Mathis, Kensaku Mori, Takahito Nakajima, Kiichiro Tsuchiya, Hideyuki Sakurai, Tatsuya Oda
Format: Article
Language:English
Published: BMC 2023-07-01
Series:BMC Cancer
Subjects:
Locally advanced pancreatic cancer
Clinical trial
Multidisciplinary treatment
Proton beam therapy
Hyperthermia
Online Access:https://doi.org/10.1186/s12885-023-11110-y

Internet

https://doi.org/10.1186/s12885-023-11110-y

Similar Items