Transgenic shRNA pigs reduce susceptibility to foot and mouth disease virus infection

Transgenic shRNA pigs reduce susceptibility to foot and mouth disease virus infection

Foot-and-mouth disease virus (FMDV) is an economically devastating viral disease leading to a substantial loss to the swine industry worldwide. A novel alternative strategy is to develop pigs that are genetically resistant to infection. Here, we produce transgenic (TG) pigs that constitutively expre...

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Bibliographic Details
Main Authors: Shengwei Hu, Jun Qiao, Qiang Fu, Chuangfu Chen, Wei Ni, Sai Wujiafu, Shiwei Ma, Hui Zhang, Jingliang Sheng, Pengyan Wang, Dawei Wang, Jiong Huang, Lijuan Cao, Hongsheng Ouyang
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-06-01
Series:eLife
Subjects:
FMDV
transgenic pig
RNAi
Online Access:https://elifesciences.org/articles/06951

Internet

https://elifesciences.org/articles/06951

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