Synthesis of Radioisotope 14C Labelled Remdesivir
To prepare the radiotracer for the pharmacokinetics study of Remdesivir, the 14C labelled Remdesivir at 4-C in pyrrolo[2,1-f][1,2,4]triazine moiety was synthesized via ten-step reaction. Firstly, nonradioactive 1H-pyrrole was formylated with N,N-dimethyl[14C]formamide and phosphorus oxychloride in d...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | zho |
| Published: |
Editorial Office of Journal of Nuclear and Radiochemistry
2025-02-01
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| Series: | He huaxue yu fangshe huaxue |
| Subjects: | |
| Online Access: | https://jnrc.xml-journal.net/cn/article/doi/10.7538/hhx.2025.47.01.0093 |