IGFBP5 promotes diabetic kidney disease progression by enhancing PFKFB3-mediated endothelial glycolysis

IGFBP5 promotes diabetic kidney disease progression by enhancing PFKFB3-mediated endothelial glycolysis

Abstract Renal inflammation is a critical pathophysiological characteristic of diabetic kidney disease (DKD). The mechanism of the inflammatory response is complicated, and there are few effective treatments for renal inflammation that can be used clinically. Insulin-like growth factor-binding prote...

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Bibliographic Details
Main Authors: Chengcheng Song, Shuqiang Wang, Zhangning Fu, Kun Chi, Xiaodong Geng, Chao Liu, Guangyan Cai, Xiangmei Chen, Di Wu, Quan Hong
Format: Article
Language:English
Published: Nature Publishing Group 2022-04-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-022-04803-y

Internet

https://doi.org/10.1038/s41419-022-04803-y

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