The Requirement of Inorganic Fe-S Clusters for the Biosynthesis of the Organometallic Molybdenum Cofactor

Iron-sulfur (Fe-S) clusters are essential protein cofactors. In enzymes, they are present either in the rhombic [2Fe-2S] or the cubic [4Fe-4S] form, where they are involved in catalysis and electron transfer and in the biosynthesis of metal-containing prosthetic groups like the molybdenum cofactor (...

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Bibliographic Details
Main Authors: Ralf R. Mendel, Thomas W. Hercher, Arkadiusz Zupok, Muhammad A. Hasnat, Silke Leimkühler
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Inorganics
Subjects:
Online Access:https://www.mdpi.com/2304-6740/8/7/43