Perampanel: New drug for treatment of refractory partial onset seizures

Perampanel (2-[2-oxo-1-phenyl-5-pyridin-2-yl-1,2-dihydropyridin-3-yl] benzonitrile hydrate) is the latest antiepileptic drugs for treatment of refractory partial onset seizures. Perampanel inhibits α-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (AMPA)-induced increase in intracellular Ca 2+ a...

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Bibliographic Details
Main Authors: Santosh Kumar Singh, Dick B. S. Brashier
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2014-01-01
Series:Muller Journal of Medical Sciences and Research
Subjects:
Online Access:http://www.mjmsr.net/article.asp?issn=0975-9727;year=2014;volume=5;issue=2;spage=195;epage=199;aulast=Singh