BEXCIS: Bayesian methods for estimating the degree of the skewness of X chromosome inactivation

BEXCIS: Bayesian methods for estimating the degree of the skewness of X chromosome inactivation

Abstract Background X chromosome inactivation (XCI) is an epigenetic phenomenon that one of two X chromosomes in females is transcriptionally silenced during early embryonic development. Skewed XCI has been reported to be associated with some X-linked diseases. There have been several methods measur...

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Bibliographic Details
Main Authors: Wen-Yi Yu, Yu Zhang, Meng-Kai Li, Zi-Ying Yang, Wing Kam Fung, Pei-Zhen Zhao, Ji-Yuan Zhou
Format: Article
Language:English
Published: BMC 2022-05-01
Series:BMC Bioinformatics
Subjects:
Skewed X chromosome inactivation
Bayesian method
Penalized Fieller’s method
Graves’ disease data
Minnesota Center for Twin and Family Research data
Online Access:https://doi.org/10.1186/s12859-022-04721-y

Internet

https://doi.org/10.1186/s12859-022-04721-y

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