A logic-incorporated gene regulatory network deciphers principles in cell fate decisions

A logic-incorporated gene regulatory network deciphers principles in cell fate decisions

Organisms utilize gene regulatory networks (GRN) to make fate decisions, but the regulatory mechanisms of transcription factors (TF) in GRNs are exceedingly intricate. A longstanding question in this field is how these tangled interactions synergistically contribute to decision-making procedures. To...

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Bibliographic Details
Main Authors: Gang Xue, Xiaoyi Zhang, Wanqi Li, Lu Zhang, Zongxu Zhang, Xiaolin Zhou, Di Zhang, Lei Zhang, Zhiyuan Li
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2024-04-01
Series:eLife
Subjects:
gene regulatory network
cell fate decision
gene regulatory logic
driving force
gene expression noise
cell dynamics
Online Access:https://elifesciences.org/articles/88742

Internet

https://elifesciences.org/articles/88742

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