Prediction of the Mechanism of Sodium Butyrate against Radiation-Induced Lung Injury in Non-Small Cell Lung Cancer Based on Network Pharmacology and Molecular Dynamic Simulations

Prediction of the Mechanism of Sodium Butyrate against Radiation-Induced Lung Injury in Non-Small Cell Lung Cancer Based on Network Pharmacology and Molecular Dynamic Simulations

BackgroundRadiation-induced lung injury (RILI) is a severe side effect of radiotherapy for non-small cell lung cancer (NSCLC) ,and one of the major hindrances to improve the efficacy of radiotherapy. Previous studies have confirmed that sodium butyrate (NaB) has potential of anti-radiation toxicity....

Full description

Bibliographic Details
Main Authors: Xiao-zhen Zhang, Mao-jian Chen, Ping-ming Fan, Ting-shi Su, Shi-xiong Liang, Wei Jiang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Oncology
Subjects:
radiation-induced lung injury
non-small cell lung cancer
network pharmacology
molecular docking
molecular dynamics simulation
sodium butyrate
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.809772/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2022.809772/full

Similar Items