The M2a Macrophage Phenotype Accompanies Pulmonary Granuloma Resolution in <i>Mmp12</i> Knock-Out Mice Instilled with Multiwall Carbon Nanotubes

The M2a Macrophage Phenotype Accompanies Pulmonary Granuloma Resolution in <i>Mmp12</i> Knock-Out Mice Instilled with Multiwall Carbon Nanotubes

Sarcoidosis is a chronic disease with unknown etiology and pathophysiology, characterized by granuloma formation. Matrix Metalloproteinase-12 (MMP12) is an elastase implicated in active granulomatous sarcoidosis. Previously, we reported that oropharyngeal instillation of multiwall carbon nanotubes (...

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Bibliographic Details
Main Authors: David Ogburn, Sophia Bhalla, Nan Leffler, Arjun Mohan, Anagha Malur, Achut G. Malur, Matthew McPeek, Barbara P. Barna, Mary Jane Thomassen
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:International Journal of Molecular Sciences
Subjects:
sarcoidosis
MMP12
PPARγ
MWCNT
granuloma
inflammation
Online Access:https://www.mdpi.com/1422-0067/22/20/11019

Internet

https://www.mdpi.com/1422-0067/22/20/11019

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