Green Synthesis of 7,8-Difluoro-6, 11-Dihydrodibenz[B,E]Thiophene-11-One of Baloxavir Marboxil -- Reducing Environmental Pollution

Baloxavir marboxil is a novel anti-influenza drug with a unique mechanism of action that can effectively treat both type A and type B influenza. Key intermediate compound 7,8-difluoro-6,11-dihydrodibenz[b,e]thiophene-11-one is not only an important component of the chemical structure of baloxavir ma...

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Bibliographic Details
Main Authors: Wang Jiaru, Ru Mengdi, Meng Zihui, Xu Zhibing
Format: Article
Language:English
Published: EDP Sciences 2023-01-01
Series:E3S Web of Conferences
Online Access:https://www.e3s-conferences.org/articles/e3sconf/pdf/2023/43/e3sconf_icemee2023_02033.pdf