High Throughput Screening of the NatureBank ‘Marine Collection’ in a <i>Haemonchus</i> Bioassay Identifies Anthelmintic Activity in Extracts from a Range of Sponges from Australian Waters

High Throughput Screening of the NatureBank ‘Marine Collection’ in a <i>Haemonchus</i> Bioassay Identifies Anthelmintic Activity in Extracts from a Range of Sponges from Australian Waters

Widespread resistance in parasitic nematodes to most classes of anthelmintic drugs demands the discovery and development of novel compounds with distinct mechanisms of action to complement strategic or integrated parasite control programs. Products from nature—which assume a diverse ‘chemical space’...

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Bibliographic Details
Main Authors: Aya C. Taki, Joseph J. Byrne, Abdul Jabbar, Kah Yean Lum, Sasha Hayes, Russell S. Addison, Kelsey S. Ramage, Andreas Hofmann, Merrick G. Ekins, Tao Wang, Bill C. H. Chang, Rohan A. Davis, Robin B. Gasser
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Molecules
Subjects:
high throughput screening
<i>Haemonchus contortus</i>
parasitic nematode
anthelmintic
marine natural products
sponge
Online Access:https://www.mdpi.com/1420-3049/26/19/5846

Internet

https://www.mdpi.com/1420-3049/26/19/5846

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