Pertussis Toxin Inhibits Encephalitogenic T-Cell Infiltration and Promotes a B-Cell-Driven Disease during Th17-EAE

Pertussis Toxin Inhibits Encephalitogenic T-Cell Infiltration and Promotes a B-Cell-Driven Disease during Th17-EAE

Pertussis toxin (PTX) is a required co-adjuvant for experimental autoimmune encephalomyelitis (EAE) induced by immunization with myelin antigen. However, PTX’s effects on EAE induced by the transfer of myelin-specific T helper cells is not known. Therefore, we investigated how PTX affects the Th17 t...

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Bibliographic Details
Main Authors: Zahra Maria, Emma Turner, Agnieshka Agasing, Gaurav Kumar, Robert C. Axtell
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:International Journal of Molecular Sciences
Subjects:
experimental autoimmune encephalomyelitis
multiple sclerosis
chemokines
Th17
B cells
Online Access:https://www.mdpi.com/1422-0067/22/6/2924

Internet

https://www.mdpi.com/1422-0067/22/6/2924

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