The Effect of Dehydroepiandrosterone Treatment on Neurogenesis, Astrogliosis and Long-Term Cocaine-Seeking Behavior in a Cocaine Self-Administration Model in Rats

The Effect of Dehydroepiandrosterone Treatment on Neurogenesis, Astrogliosis and Long-Term Cocaine-Seeking Behavior in a Cocaine Self-Administration Model in Rats

Cocaine addiction is an acquired behavioral state developed in vulnerable individuals after cocaine exposure. It is characterized by compulsive drug-seeking and high vulnerability to relapse even after prolonged abstinence, associated with decreased neurogenesis in the hippocampus. This addictive st...

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Bibliographic Details
Main Authors: Hadas Ahdoot-Levi, Ofri Croitoru, Tzofnat Bareli, Einav Sudai, Hilla Peér-Nissan, Avi Jacob, Iris Gispan, Rachel Maayan, Abraham Weizman, Gal Yadid
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Neuroscience
Subjects:
addiction
neurogensis
astrogliosis
cocaine
self-administration
DHEA
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2021.773197/full

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https://www.frontiersin.org/articles/10.3389/fnins.2021.773197/full

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