Myocyte-specific enhancer factor 2c triggers transdifferentiation of adipose tissue-derived stromal cells into spontaneously beating cardiomyocyte-like cells

Myocyte-specific enhancer factor 2c triggers transdifferentiation of adipose tissue-derived stromal cells into spontaneously beating cardiomyocyte-like cells

Abstract Cardiomyocyte regeneration is limited in adults. The adipose tissue-derived stromal vascular fraction (Ad-SVF) contains pluripotent stem cells that rarely transdifferentiate into spontaneously beating cardiomyocyte-like cells (beating CMs). However, the characteristics of beating CMs and th...

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Bibliographic Details
Main Authors: Shinichiro Takashima, Soichiro Usui, Oto Inoue, Chiaki Goten, Kosei Yamaguchi, Yusuke Takeda, Shihe Cui, Yoshio Sakai, Kenshi Hayashi, Kenji Sakata, Masa-aki Kawashiri, Masayuki Takamura
Format: Article
Language:English
Published: Nature Portfolio 2021-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-80848-3

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https://doi.org/10.1038/s41598-020-80848-3

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