Comparison of lentiviral and sleeping beauty mediated αβ T cell receptor gene transfer.

Comparison of lentiviral and sleeping beauty mediated αβ T cell receptor gene transfer.

Transfer of tumour antigen-specific receptors to T cells requires efficient delivery and integration of transgenes, and currently most clinical studies are using gamma retroviral or lentiviral systems. Whilst important proof-of-principle data has been generated for both chimeric antigen receptors an...

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Bibliographic Details
Main Authors: Anne-Christine Field, Conrad Vink, Richard Gabriel, Roua Al-Subki, Manfred Schmidt, Nicholas Goulden, Hans Stauss, Adrian Thrasher, Emma Morris, Waseem Qasim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3695921?pdf=render

Internet

http://europepmc.org/articles/PMC3695921?pdf=render

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