The effect of anti-IL5 monoclonal antibodies on regulatory and effector T cells in severe eosinophilic asthma

The effect of anti-IL5 monoclonal antibodies on regulatory and effector T cells in severe eosinophilic asthma

Introduction: Biological treatments have redesigned the clinical management of severe eosinophilic asthmatic (SA) patients. Despite emerging evidence supporting the role of natural Killer (NK), and T regulatory cells (Treg) in the pathogenesis of asthma, no data is available on the effects of anti-I...

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Bibliographic Details
Main Authors: Laura Bergantini, Tommaso Pianigiani, Miriana d’Alessandro, Sara Gangi, Behar Cekorja, Elena Bargagli, Paolo Cameli
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Benralizumab
Mepolizumab
Severe asthma
Regulatory T cells
Immune checkpoints
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332223011824

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http://www.sciencedirect.com/science/article/pii/S0753332223011824

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