Engineering enhanced chimeric antigen receptor-T cell therapy for solid tumors

The early clinical success and subsequent US Food and Drug Administration approval of chimeric antigen receptor (CAR)-T cell therapy for leukemia and lymphoma affirm that engineered T cells can be a powerful treatment for hematologic malignancies. Yet this success has not been replicated in solid tu...

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Bibliographic Details
Main Authors: A. Neeser, R. Ramasubramanian, C. Wang, L. Ma
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:Immuno-Oncology and Technology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2590018823000138