Synthetic multivalent antifungal peptides effective against fungi.

Synthetic multivalent antifungal peptides effective against fungi.

Taking advantage of the cluster effect observed in multivalent peptides, this work describes antifungal activity and possible mechanism of action of tetravalent peptide (B4010) which carries 4 copies of the sequence RGRKVVRR through a branched lysine core. B4010 displayed better antifungal propertie...

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Bibliographic Details
Main Authors: Rajamani Lakshminarayanan, Shouping Liu, Jianguo Li, Muruganantham Nandhakumar, Thet Tun Aung, Eunice Goh, Jamie Ya Ting Chang, Padhmanaban Saraswathi, Charles Tang, Siti Radiah Binte Safie, Lim Yih Lin, Howard Riezman, Zhou Lei, Chandra S Verma, Roger W Beuerman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24498363/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24498363/?tool=EBI

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