Synthesis, Chiral Resolution and Enantiomers Absolute Configuration of 4-Nitropropranolol and 7-Nitropropranolol

Synthesis, Chiral Resolution and Enantiomers Absolute Configuration of 4-Nitropropranolol and 7-Nitropropranolol

We recently identified 6-nitrodopamine and other nitro-catecholamines (6-nitrodopa, 6-nitroadrenaline), indicating that the endothelium has the ability to nitrate the classical catecholamines (dopamine, noradrenaline, and adrenaline). In order to investigate whether drugs could be subject to the sam...

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Bibliographic Details
Main Authors: Rosa Sparaco, Antonia Scognamiglio, Angela Corvino, Giuseppe Caliendo, Ferdinando Fiorino, Elisa Magli, Elisa Perissutti, Vincenzo Santagada, Beatrice Severino, Paolo Luciano, Marcello Casertano, Anna Aiello, Gilberto De Nucci, Francesco Frecentese
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Molecules
Subjects:
4-nitropropranolol
7-nitropropranolol
chiral HPLC
NMR absolute configuration assignment
Riguera’s method
Online Access:https://www.mdpi.com/1420-3049/28/1/57

Internet

https://www.mdpi.com/1420-3049/28/1/57

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