Association of childhood BMI trajectory with post-adolescent and adult lung function is mediated by pre-adolescent DNA methylation

Association of childhood BMI trajectory with post-adolescent and adult lung function is mediated by pre-adolescent DNA methylation

Abstract Background Body mass index (BMI) has been shown to be associated with lung function. Recent findings showed that DNA methylation (DNAm) variation is likely to be a consequence of changes in BMI. However, whether DNAm mediates the association of BMI with lung function is unknown. We examined...

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Bibliographic Details
Main Authors: Rutu Rathod, Hongmei Zhang, Wilfried Karmaus, Susan Ewart, Fawaz Mzayek, S. Hasan Arshad, John W. Holloway
Format: Article
Language:English
Published: BMC 2022-07-01
Series:Respiratory Research
Subjects:
BMI trajectory
DNA methylation
IOWBC
Lung function
Online Access:https://doi.org/10.1186/s12931-022-02089-4

Internet

https://doi.org/10.1186/s12931-022-02089-4

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