Adaptive and innate immune responses in multiple sclerosis with anti-CD20 therapy: Gene expression and protein profiles

Adaptive and innate immune responses in multiple sclerosis with anti-CD20 therapy: Gene expression and protein profiles

BackgroundAnti-CD20 is a highly effective therapy for multiple sclerosis (MS), a disease with multiple abnormalities in function of B and T cells and innate immune cells. Anti-CD20 therapy depletes B cells, which alters antibody production and has diverse effects on B cell immunity. These changes po...

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Bibliographic Details
Main Authors: Chloe C. Fong, Julian Spencer, Quentin Howlett-Prieto, Xuan Feng, Anthony T. Reder
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Neurology
Subjects:
anti-CD20 therapy
B cell
multiple sclerosis
ocrelizumab
T cell
TLR
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2023.1158487/full

Internet

https://www.frontiersin.org/articles/10.3389/fneur.2023.1158487/full

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