Elucidating the susceptibility to breast cancer: an in-depth proteomic and transcriptomic investigation into novel potential plasma protein biomarkers

Elucidating the susceptibility to breast cancer: an in-depth proteomic and transcriptomic investigation into novel potential plasma protein biomarkers

Objectives: This study aimed to identify plasma proteins that are associated with and causative of breast cancer through Proteome and Transcriptome-wide association studies combining Mendelian Randomization.Methods: Utilizing high-throughput datasets, we designed a two-phase analytical framework aim...

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Bibliographic Details
Main Authors: Yang Wang, Kexin Yi, Baoyue Chen, Bailin Zhang, Gao Jidong
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Molecular Biosciences
Subjects:
proteome-wide association study
transcriptome-wide association study
plasma proteins
mendelian randomization
breast cancer
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2023.1340917/full

Internet

https://www.frontiersin.org/articles/10.3389/fmolb.2023.1340917/full

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