Exportin-1-Dependent Nuclear Export of DEAD-box Helicase DDX3X is Central to its Role in Antiviral Immunity

Exportin-1-Dependent Nuclear Export of DEAD-box Helicase DDX3X is Central to its Role in Antiviral Immunity

DEAD-box helicase 3, X-linked (DDX3X) regulates the retinoic acid-inducible gene I (RIG-I)-like receptor (RLR)-mediated antiviral response, but can also be a host factor contributing to the replication of viruses of significance to human health, such as human immunodeficiency virus type 1 (HIV-1). T...

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Bibliographic Details
Main Authors: Steven M. Heaton, Sarah C. Atkinson, Melissa N. Sweeney, Sundy N. Y. Yang, David A. Jans, Natalie A. Borg
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Cells
Subjects:
ddx3x
nuclear export
exportin-1
crm1
nes
antiviral immunity
parainfluenza virus
Online Access:https://www.mdpi.com/2073-4409/8/10/1181

Internet

https://www.mdpi.com/2073-4409/8/10/1181

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