Structural insights into the PrpTA toxin–antitoxin system in Pseudoalteromonas rubra

Structural insights into the PrpTA toxin–antitoxin system in Pseudoalteromonas rubra

Bacteria could survive stresses by a poorly understood mechanism that contributes to the emergence of bacterial persisters exhibiting multidrug tolerance (MDT). Recently, Pseudoalteromonas rubra prpAT module was found to encode a toxin PrpT and corresponding cognate antidote PrpA. In this study, we...

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Bibliographic Details
Main Authors: Chenchen Wang, Chuanying Niu, Khan Muhammad Hidayatullah, Lu Xue, Zhongliang Zhu, Liwen Niu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Microbiology
Subjects:
PrpTA
toxin–antitoxin system
MDT
conformational changes
protein oligomerization
plasmid replication
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.1053255/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2022.1053255/full

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