Lamellar granule secretion starts before the establishment of tight junction barrier for paracellular tracers in mammalian epidermis.

Lamellar granule secretion starts before the establishment of tight junction barrier for paracellular tracers in mammalian epidermis.

Defects in epidermal barrier function and/or vesicular transport underlie severe skin diseases including ichthyosis and atopic dermatitis. Tight junctions (TJs) form a single layered network in simple epithelia. TJs are important for both barrier functions and vesicular transport. Epidermis is strat...

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Bibliografski detalji
Glavni autori: Akemi Ishida-Yamamoto, Mari Kishibe, Masamoto Murakami, Masaru Honma, Hidetoshi Takahashi, Hajime Iizuka
Format: Članak
Jezik:English
Izdano: Public Library of Science (PLoS) 2012-01-01
Serija:PLoS ONE
Online pristup:http://europepmc.org/articles/PMC3273471?pdf=render

Internet

http://europepmc.org/articles/PMC3273471?pdf=render

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