Exosome derived from tumor-associated macrophages: biogenesis, functions, and therapeutic implications in human cancers

Exosome derived from tumor-associated macrophages: biogenesis, functions, and therapeutic implications in human cancers

Abstract Tumor-associated macrophages (TAMs), one of the most abundant immune cell types in the tumor microenvironment (TME), account for approximately 50% of the local hematopoietic cells. TAMs play an important role in tumorigenesis and tumor development through crosstalk between various immune ce...

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Bibliographic Details
Main Authors: Manli Zhou, Xiaoyun He, Cheng Mei, Chunlin Ou
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Biomarker Research
Subjects:
Tumor-associated macrophages
Exosomes
Tumor microenvironment
Metabolic reprogramming
Liquid biopsy
Therapeutic target
Online Access:https://doi.org/10.1186/s40364-023-00538-w

Internet

https://doi.org/10.1186/s40364-023-00538-w

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