Redox Active α-Lipoic Acid Differentially Improves Mitochondrial Dysfunction in a Cellular Model of Alzheimer and Its Control Cells

Redox Active α-Lipoic Acid Differentially Improves Mitochondrial Dysfunction in a Cellular Model of Alzheimer and Its Control Cells

Introduction: Alpha lipoic acid (ALA) is a sulphur-containing organic compound, derived from octanoic acid, and an important cofactor for mitochondrial respiratory enzymes. It has strong antioxidant properties that improve mitochondrial function. We investigated if ALA improves mitochondrial dysfunc...

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Bibliographic Details
Main Authors: Fabian Dieter, Carsten Esselun, Gunter P. Eckert
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:International Journal of Molecular Sciences
Subjects:
alpha lipoic acid
Alzheimer disease
mitochondria
ROS
mitochondria dysfunction
respiratory chain
Online Access:https://www.mdpi.com/1422-0067/23/16/9186

Internet

https://www.mdpi.com/1422-0067/23/16/9186

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