Phenotypic characterization of prostate cancer LNCaP cells cultured within a bioengineered microenvironment.

Biophysical and biochemical properties of the microenvironment regulate cellular responses such as growth, differentiation, morphogenesis and migration in normal and cancer cells. Since two-dimensional (2D) cultures lack the essential characteristics of the native cellular microenvironment, three-di...

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Bibliographic Details
Main Authors: Shirly Sieh, Anna V Taubenberger, Simone C Rizzi, Martin Sadowski, Melanie L Lehman, Anja Rockstroh, Jiyuan An, Judith A Clements, Colleen C Nelson, Dietmar W Hutmacher
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3434144?pdf=render