The influence of oxygen and oxidative stress on de novo acquisition of antibiotic resistance in E. coli and Lactobacillus lactis

The influence of oxygen and oxidative stress on de novo acquisition of antibiotic resistance in E. coli and Lactobacillus lactis

Abstract Background Bacteria can acquire resistance through DNA mutations in response to exposure to sub-lethal concentrations of antibiotics. According to the radical-based theory, reactive oxygen species (ROS), a byproduct of the respiratory pathway, and oxidative stress caused by reactive metabol...

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Bibliographic Details
Main Authors: Wenxi Qi, Martijs J. Jonker, Lisa Teichmann, Meike Wortel, Benno H. ter Kuile
Format: Article
Language:English
Published: BMC 2023-10-01
Series:BMC Microbiology
Subjects:
Reactive oxygen species
De novo resistance
Antimicrobial resistance
Whole genome sequencing
Reactive metabolic byproducts
Online Access:https://doi.org/10.1186/s12866-023-03031-4

Internet

https://doi.org/10.1186/s12866-023-03031-4

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