Structural Diversity of Sense and Antisense RNA Hexanucleotide Repeats Associated with ALS and FTLD

The hexanucleotide expansion GGGGCC located in <i>C9orf72</i> gene represents the most common genetic cause of amyotrophic lateral sclerosis (ALS) and frontotemporal lobar dementia (FTLD). Since the discovery one of the non-exclusive mechanisms of expanded hexanucleotide G<sub>4<...

Full description

Bibliographic Details
Main Authors: Tim Božič, Matja Zalar, Boris Rogelj, Janez Plavec, Primož Šket
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/25/3/525