Structural Diversity of Sense and Antisense RNA Hexanucleotide Repeats Associated with ALS and FTLD

Structural Diversity of Sense and Antisense RNA Hexanucleotide Repeats Associated with ALS and FTLD

The hexanucleotide expansion GGGGCC located in <i>C9orf72</i> gene represents the most common genetic cause of amyotrophic lateral sclerosis (ALS) and frontotemporal lobar dementia (FTLD). Since the discovery one of the non-exclusive mechanisms of expanded hexanucleotide G<sub>4<...

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Bibliographic Details
Main Authors: Tim Božič, Matja Zalar, Boris Rogelj, Janez Plavec, Primož Šket
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Molecules
Subjects:
nmr
rna
als
ftld
<i>c9orf72</i>
Online Access:https://www.mdpi.com/1420-3049/25/3/525

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