Protective effect of resveratrol against oxygen–glucose deprivation in organotypic hippocampal slice cultures: Involvement of PI3-K pathway

Protective effect of resveratrol against oxygen–glucose deprivation in organotypic hippocampal slice cultures: Involvement of PI3-K pathway

Here we investigated the neuroprotective effect of resveratrol in an in vitro model of ischemia. We used organotypic hippocampal cultures exposed to oxygen–glucose deprivation (OGD). In OGD-vehicle exposed cultures, about 46% of the hippocampus was labeled with PI, indicating a robust percentage of...

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Bibliographic Details
Main Authors: Lauren L. Zamin, Patrícia Dillenburg-Pilla, Ricardo Argenta-Comiran, Ana Paula Horn, Fabrício Simão, Melissa Nassif, Daniéli Gerhardt, Rudimar L. Frozza, Christianne Salbego
Format: Article
Language:English
Published: Elsevier 2006-10-01
Series:Neurobiology of Disease
Subjects:
Neuroprotection
Resveratrol
Oxygen–glucose deprivation
Hippocampus
Organotypic culture
Akt
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996106001446

Internet

http://www.sciencedirect.com/science/article/pii/S0969996106001446

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